Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2269 |
Pirinixic Acid
Wy-14643,NSC 310038,匹立尼酸 |
PPAR | DNA Damage/DNA Repair; Metabolism |
Pirinixic Acid (NSC 310038) 是一种过氧化物酶体增殖剂,可激活特定的过氧化物酶体增殖物激活受体 (PPAR)。它对鼠的PPARα和 PPARγ 的EC50值分别为 0.63 和 32 μM,对人的PPARα、PPARγ 和 PPARδ 的EC50值分别为 5.0 、60 和 35 μM。 | |||
T37905 | Hexanoyl Glycine | ||
Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during... |